| Description: |
Schematic of an artificial membrane, across which a voltage forces an ionized fluid through the nanopore. Nucleotides on a strand of DNA are first tagged with different-sized polymers, and then the strand is passed near the nanopore opening, where a polymerase cleaves the polymers and passes them one by one through the nanopore. As they pass, the pore produces a unique ionic current blockade signature due to the tag's distinct chemical structure, thereby determining DNA sequence.
*PML
See also http://www.nist.gov/pml/div683/dna-100212.cfm.
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